Sex-related differences in pharmacokinetics and pharmacodynamics of frequently prescribed drugs: a review of the literature

A Farkouh, T Riedl, R Gottardi, M Czejka… - Advances in …, 2020 - Springer
… in men and women [4]. Importantly, there are also significant differences between men and
women in … In contrast, women benefit more from opioids that interact with the κ-receptor, eg …

[HTML][HTML] The pharmacodynamics of antipsychotic drugs in women and men

MV Seeman - Frontiers in psychiatry, 2021 - frontiersin.org
… of differences in pharmacokinetics and pharmacodynamics, clinically relevant adverse drug
reactions differ between men and women (… suggests that the biology of sex and the impact of …

The role of gender pharmacogenetics in the personalization of drug treatment

E Cecchin, B Posocco, S Mezzalira… - Journal of …, 2023 - ASPET
… on the interaction between gender and pharmacogenetics in … Network for Drug Safety, and
additional scientific consortia are … The most striking difference between males and females is …

[HTML][HTML] Sex differences in pharmacokinetics predict adverse drug reactions in women

I Zucker, BJ Prendergast - Biology of sex differences, 2020 - bsd.biomedcentral.com
scientific community [9]. Regulatory agencies have historically paid insufficient attention to
differences between women and men in … in women and men and considers sex differences in …

Let's talk about sex: Differences in drug therapy in males and females

CM Madla, FKH Gavins, HA Merchant, M Orlu… - Advanced Drug Delivery …, 2021 - Elsevier
… as a biological variable in drug delivery, pharmacokinetic … attention to differences between
women and men in terms of … that differences in communication tactics between males and …

Pharmacology, Pharmacogenetics, and Pharmacoepidemiology: Three P's of Individualized Therapy

S Dawood - Pharmacogenetics of Breast Cancer, 2020 - taylorfrancis.com
… a product of the gene environment interaction is also vital to our … Both the pharmacokinetic
and pharmacodynamic components of … Pharmacogenetics of tamoxifen bio transformation is …

UGT1A3 and sex are major determinants of telmisartan pharmacokinetics—a comprehensive pharmacogenomic study

P Hirvensalo, A Tornio, T Launiainen… - Clinical …, 2020 - Wiley Online Library
pharmacokinetics. The aim of this study was to evaluate how variations in 379 pharmacokinetic
genes … showed only a relatively small difference between UGT1A3*2 homozygotes and …

Addressing ancestry and sex bias in pharmacogenomics

M Corpas, MK Siddiqui, O Soremekun… - Annual Review of …, 2023 - annualreviews.org
… An example in pharmacogenomics where biological sex appears … and safety of drugs,
health-care interactions, and behaviors. … Profiling of warfarin pharmacokinetics-associated genetic …

Genetic polymorphisms associated with the pharmacokinetics, pharmacodynamics and adverse effects of olanzapine, aripiprazole and risperidone

P Soria-Chacartegui, G Villapalos-García… - Frontiers in …, 2021 - frontiersin.org
Pharmacogenetics studies the influence of genetic variability on drug response. Its aim is
to select "the right drug, at the right dose, for the right patient," predicting the tolerance and …

Gender based differences, pharmacogenetics and adverse events in chronic pain management

B Planelles, C Margarit, MM Inda, P Ballester… - … pharmacogenomics …, 2020 - nature.com
… , pharmacological differences between women and men might … the market presented greater
health risks for women [7,8,9]. In … , differences in pharmacokinetics and pharmacodynamics, …